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IMPORTANTE

IMPORTANTE Global and Semi-Global Alignments: The Needleman-Wunsch Algorithm preferes the global alignment, but we can change it to make it return the optimal solution for local alignment:
NOTE: How the two alignments are extreamly different.

We can add two new rules that states

  • The orizontal steps at the last row do not add a malus to the score
  • Both rows and columns are initialized at

With these rules we are basicly removing the malus given to initial and final gaps.


Slides with Notes

IMPORTANTE Global and Semi-Global Alignments: The Needleman-Wunsch Algorithm preferes the global alignment, but we can change it to make it return the optimal solution for local alignment:
NOTE: How the two alignments are extreamly different.

We can add two new rules that states

  • The orizontal steps at the last row do not add a malus to the score
  • Both rows and columns are initialized at

With these rules we are basicly removing the malus given to initial and final gaps.