Questions
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IMPORTANTE
IMPORTANTE Drug Design is divided into Discovery and Testing.
Discovery:
- Target Identification (what does the new drug have to do)
- Discovery and optimization of “lead” compounds
- Toxicology and Pharmacokinetics (study of absorption, distribution, metabolism and elimination of drugs)
Testing:
- Pre-Clinical test.
- Clinical trials.
IMPORTANTE Target Identification on Drug Design: Consist of isolating a biological molecule that is essential for the survival or the proliferation of a particular agent called a “pathogen”, responsible for a disease. ==Most of the time the target is a protein== After we have identified the target we search for a molecule that binds to the target and inhibits its activity
IMPORTANTE ~Ex.: HIV Virus
IMPORTANTE ~Ex.:
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Slides with Notes
IMPORTANTE Drug Design is divided into Discovery and Testing.
Discovery:
- Target Identification (what does the new drug have to do)
- Discovery and optimization of “lead” compounds
- Toxicology and Pharmacokinetics (study of absorption, distribution, metabolism and elimination of drugs)
Testing:
- Pre-Clinical test.
- Clinical trials.
IMPORTANTE Target Identification on Drug Design: Consist of isolating a biological molecule that is essential for the survival or the proliferation of a particular agent called a “pathogen”, responsible for a disease. ==Most of the time the target is a protein== After we have identified the target we search for a molecule that binds to the target and inhibits its activity
IMPORTANTE ~Ex.: HIV Virus
IMPORTANTE ~Ex.:
