BI - Alignment Scores

Questions

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IMPORTANTE

IMPORTANTE Alignment Scores Useful numbers to evaluate numerically how good the alignment is:

• $S$ : alignment score, calculated with a defined score function.
• $E$ : proportioanl to the expected number of random sequences with an alignment score $\ge S$. ($E\le 10^{-3}$ is statistically significant, but we often find $E\le 10^{-50}$, much better)
• $P$ : represents the proability that the database contains one or more random sequences with score $\ge S$.

Usign $E$ and $P$ we can infer how much the result is obtained by chance

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Slides with Notes

IMPORTANTE Alignment Scores Useful numbers to evaluate numerically how good the alignment is:

• $S$ : alignment score, calculated with a defined score function.
• $E$ : proportioanl to the expected number of random sequences with an alignment score $\ge S$. ($E\le 10^{-3}$ is statistically significant, but we often find $E\le 10^{-50}$, much better)
• $P$ : represents the proability that the database contains one or more random sequences with score $\ge S$.

Usign $E$ and $P$ we can infer how much the result is obtained by chance